13 December 2025

How To Beat Osquio In Expedition 33

By newsgame


Esquie is a notable character in Clair Obscur: Expedition 33, thanks to his warm and humorous persona, but players may not know that he has an evil cousin called Osquio.

Osquio in Expedition 33 is a unique boss challenge that shows the power of Esquie’s kind. Defeating Osquio in E33 comes with precious rewards like a Perfect Chroma Catalyst, but the best part is the costume this boss unlocks.

clair-obscur-expedition-33-esquie-header

How to Unlock All Esquie Abilities in Clair Obscur Expedition 33

Esquie becomes one of your best allies in Clair Obscur: Expedition 33, not just for his whimsical wit but his abilities as well.

Osquio Location In Clair Obscur Expedition 33

clair-obscur-expedition-33-e33-how-beat-osquio-tips-location-reward-guide-skill-dodge

Osquio is located in Verso’s Draft in Clair Obscur: Expedition 33. He resides in a special domain called Root of All Evil.

clair-obscur-expedition-33-e33-how-beat-osquio-tips-location-reward-guide-skill-dodge - reverie path

After reaching Reverie Path, which is beyond the Gestral’s carnival area, players should see a Gestral merchant nearby.

clair-obscur-expedition-33-e33-how-beat-osquio-tips-location-reward-guide-skill-dodge - gestral merchant and osquio location

Overlooking the Expedition 33 merchant is Osquio’s home, Root of All Evil.

clair-obscur-expedition-33-e33-how-beat-osquio-tips-location-reward-guide-skill-dodge - use train

Go closer, then use the train to reach Osquio.

clair-obscur-expedition-33-e33-how-beat-osquio-tips-location-reward-guide-skill-dodge - root of all evil area guide

Once inside, you’ll soon find an expedition flag to rest at. Look ahead for a set of stairs leading to an arena-like area. After approaching the place, a cutscene with Osquio will play, commencing the boss fight.

How To Beat Osquio In Clair Obscur Expedition 33

Osquio’s boss fight in Expedition 33 has two phases. Apart from his massive HP pool and fast attacks, the boss fight is pretty easy. Here are some things worth noting:

  • After entering Phase 2, Osquio’s hits will apply Barbapapa if they land, so make sure to prioritize dodging.
  • Barbapapa causes attacks and skills to deal 1 DMG, as long as the stack exists. Use multi-hit attacks to remove it quickly. Aimed Shots will not reduce Barbapapa debuff.
  • After you beat Osquio in Phase 2, he will initiate a Gradient attack that can wipe out the team. Make sure to time the Gradient counter; otherwise, you’ll lose the fight.

Osquio Skills In Expedition 33

Prompt

Osquio’s Attack

Osquio has very very strong fists

7 hits. Osquio lights his two fists before performing three consecutive hits. He briefly pauses before hitting three more times, jumping after the third hit. Then, he smashes down for his final hit.

Osquio thinks he is the fastest ball

6 hits. Osquio takes his time to roll. He jumps and lands back down, then begins hitting after. He does all six hits in a quick succession.

Time for a spin spin

Osquio removes all the debuffs on himself and regains all his HP. This marks the beginning of the second phase.

Osquio summons his little friends

11 hits. Osquio summons five masks. The masks shoot separately in quick succession. There’s a little rhythm you can follow to dodge them. Then, all five masks will shoot together. Afterward, Osquio jumps, and the masks will fall on the team one by one.

Osquio is flying gracefully

4 hits. Osquio floats above the team, then begins hitting twice quickly. There’s a brief pause before he body slams, bounces up, then slams down again.

Osquio prepares a drop kick

6 hits + Gradient hit. Shoots from his belt, then teleports to the team before punching down twice. Then, Osquio warps to the side, sliding through the team to hit twice. He rolls in the air before shooting from his belt again, then he does a Gradient hit, which requires a Gradient counter to avoid.

Osquio goes Pew Pew Pew

12 hits. Shoots from his belt. The first two shots are slow, then he quickly hits three and six more times. Finally, his belt acts up, and hits one final time after a pretty long delay.

Osquio decides to destroy the world. Bye bye

1 Gradient hit. Osquio charges up before hitting his ball of Void, starting the Gradient attack indicator. Press the gradient counter shortly before or right when the ball hits the ground.

Osquio Boss Fight Reward In Clair Obscur Expedition 33

clair-obscur-expedition-33-e33-how-beat-osquio-tips-location-reward-guide-skill-dodge-defeat - rewards

Here are the rewards from the Osquio boss fight in Expedition 33:

A merchant also appears near the flag after you win. This merchant sells Osquio outfit and hairstyle for the other characters.

Osquio’s outfit enables a unique animation when players run. Although the costume comes in a set of outfits and hairstyles, just wearing the outfit is enough to experience the Osquio-style movement. Esquie’s costume also unlocks a unique movement animation, but it’s not as grand as Osquio’s.


Clair Obscur: Expedition 33 Tag Page Cover Art


Released

April 24, 2025

ESRB

Mature 17+ / Blood and Gore, Strong Language, Suggestive Themes, Violence

Developer(s)

Sandfall Interactive

Publisher(s)

Kepler Interactive