10 March 2026

Mewgenics Mutation Guide

By newsgame

In Mewgenics, mutations are not just variations that show up on your cat’s body… they are actually signs of various buffs or debuffs. While strays and retired cats usually come with variants that are completely random, you can specifically work on creating felines with your desired effect via the breeding system or dropping them in the mutation room.

If you’re wondering how many types of modifications a cat can have in the game, here’s a quick peek at it:

Body
Head
Tail
Leg
Eye
Eyebrow
Ear
Mouth
Fur

Birth Defects are also mutations, but they mostly have negative effects that can glow down your units.

For those interested, the next sections will walk you through all the methods to snag mutant felines, along with the main variants in Mewgenics.

All Class Collars in Mewgenics (& How to Get Them)

Find out here all the class collars available in Mewgenics, how to acquire each one, and tips for choosing the right classes for your team.

How to Get Mutations in Mewgenics

Players can farm mutations in one of four ways:

Take in Stray Cats

At the start of every day, a stray walks to your house. It could be a mutant stray, which you can identify by looking at its appearance or checking its profile. However, this method is heavily RNG-dependent, but it remains the way early on.

Create a Mutation Room

Next, you can build a mutation room in your house to give your feline a chance to evolve every night. To do so, upgrade your house by sending retired cats to Frank to unlock extra rooms, one of which can be set aside specifically for this purpose. Then, fill it with high-mutation furniture, which you can purchase from Baby Frank’s shop. These are the best ones to grab:

Furniture	Mutation Stats
Brain of Glorg (Rare)	+8
Ethereal Skull (Rare)	+8
Brain of Glorg	+4
Ethereal Skull	+4
Ooze Canister (Rare)	+4
Toxic Waste (Rare)	+4

If the items you need aren’t in stock, check back every Sunday for fresh inventory, or collect furniture boxes and chests during your runs. At the end of each night, units inside the room have a chance to automatically gain a modification. This method can push your cats to reach up to 15 mutations.

Complete Adventures

When out on runs, your cats naturally pick up various effects (some good, some bad). The choices you make during adventure events can change your cat’s look and stats, so just make sure to successfully retire them to add them to your roster. Equipping certain weapons and trinkets from battles, like the Uranium Rod and Cancer, can also alter your cat in unexpected ways.

‎How to Gain Mana Fast in Mewgenics

Players wondering how to restore their cats’ Mana in Mewgenics can use this guide.

Spread the Genes

Once you have units with the best mutations, you can breed them to pass down their traits to others. To make breeding successful, you’ll need a dedicated room with high comfort and stimulation (high health is a plus). Simply leave pairs there and end the night. New kittens will inherit their parents’ modifications. Remember to have enough food, so your cats don’t end up starving and ruining the night.

All Body Mutations in Mewgenics

Mutation	Stats/Ability
Crag	+1 Constitution
Stormcloud	+1 Thorns
Croissant	+1 Brace
Pinecone	+2 Shield
Smiling Blob	+1 Constitution
Swollen Kitty	+1 Luck
Square	+1 Constitution
Splatter	+1 Charisma
Quartz	+1 Kinetic Spikes
Defected Flesh	+1 Charisma
Crowned Bean	+5 Shield
Turtle Shell	+5 Shield -1 Speed
Snail Shell	+10 Shield -2 Speed
Circuitry	+1 Speed +1 Intelligence
Tailbone	+12 Shield -3 Constitution
Viscera	+1 Strength +1 Constitution -1 Intelligence
Fur Ball	+2 Thorns -1 Charisma
Catbean	+2 Luck -1 Constitution
Two Cats Fused Together	+2 Luck -1 Charisma
Evil Kitty	+2 Luck -1 Strength
Flipped Cat	+2 Constitution -3 Speed
Rump	+1 Speed -2 Constitution
Potato Figure	+1 Constitution +1 Attack
Coin Bag	Spawn coins
Stripes on Body	Summons a Charmed Kitten when the cat dies
Meat Chunks	Gains any random stat buff
Backpack	Receives a consumable item at the end of each battle
Spores	Spawns a Charmed Fly each turn (25% chance)
Eyeball	+1 Range after a kill
Curled Up Figure	When hurt, you trample on a random tile

Guess the games from the emojis.

Easy (120s)Medium (90s)Hard (60s)

All Head Mutations in Mewgenics

Mutation	Stats/Ability
Square	+1 Constitution
Molecule	+1 Intelligence
Half Moon	+2 Luck
Rear Skull	+1 Charisma
Dripping Brain	+1 Charisma
Pricklebrain	+1 Thorns.
Obsidian	+2 Shield
Triangle	+1 Intelligence
Bean	+5% dodge chance
Mushroom	+1 Range
Cat	+2 Intelligence -3 Charisma
Flipped Heart	+2 Dexterity -1 Speed
Oval	+2 Dexterity -1 Constitution / -1 Charisma
Tear	+2 Dexterity -1 Intelligence
Lower Tooth	+2 Dexterity -1 Strength
Apple	+2 Intelligence -1 Dexterity
Jelly Fish	+2 Charisma -1 Luck
Open Brain	+2 Bruise +1 Intelligence (permanently)
Clover	+2 Speed -1 Charisma
Kitty Figure	+2 Luck -1 random stat
Lump	+1 Strength +1 Constitution -1 Intelligence
Smiley Head	+2 Constitution -1 random stat
Capsule	+1 Range +1 Melee Reach
Mickey Head	+1 Movement Range (only when your cat is wet)
Coin Bag	Drops a coin after being targeted
Magnet	Hooks enemies after using a basic attack
Poop	Spawns a poop after taking a hit
Round	Exchanges the highest and lowest stats at the start of every fight
Chunks	Receives any random stat buff
Button	Inflicts fear on enemies (5% chance)
Acorn	Gains immunity to ice
Lazybob	+1 Turn at the beginning of every fight

All Tail Mutations in Mewgenics

Mutation	Stats/Ability
Worm	+1 Dexterity
Claw	+1 Strength
Beaded Tail	Inflicts poison with your basic attack
Prickletail	+1 Thorns
Swirl	+1 Dexterity
Dough Ball	+1 Constitution
Curly Tail	+1 Speed
Hand	+1 Basic Attack (10% chance)
Wings	+2 Speed
Cat Head (grey)	+1 Intelligence
Cat Head (beige)	+5% Dodge Chance +1 Luck
Broken Glass	+1 Bleed +2 Bleed Thorns
Snake	Poisons any unit that engages you
Bone	Revive a unit with 50 HP (10% chance)
Water Pipe	Create water tiles with your basic attack
Sausage Poop	Spawns a poop after taking a hit
Maggot	Summon a Maggot when you get hurt
Tall Grass	Spawns Tall Grass on a random tile after ending your turn (25% chance)
Leaf	Being attacked triggers a poison attack that knocks enemies back
Shampoo Ginger Lily	Inflict poison with your basic attack
Spring	Pushes enemies back